NEXT GENERATION FERTILITY TECH

Separating Winning
Sperm in Alliance
with Nature

ABOUT
Molecule 46

Molecule 46 Ltd. is a biotech spin-off offering a unique patented technology for the diagnostic and separation of undamaged sperm, delivering a revolutionary solution to human infertility through assisted reproduction and enhanced livestock breeding with high-quality insemination doses.

The technology, based on the principles of natural fertilization, selects sperm with an intact acrosome, undamaged DNA, and progressive motility — increasing success rates of assisted reproduction methods including ICSI. It also enables freezing of selected sperm, benefiting infertile men, oncology patients, and healthy men in preventive sperm banking programs.

The company brings an innovative approach with a strong IP position and robust scientific research. The clear regulatory pathway is strengthened by an internationally recognised founder with a strong academic track record and proven founder/market fit for a large and fast-growing market. The technology further extends to livestock breeding, enabling high-quality insemination doses and in vitro embryo production for embryo transfer.

This project offers real social impact as well as endorsement from buyers and users.

 

HUMAN
Application

ASSISTED REPRODUCTION
Increase of sperm quality
and fertilization success

CRYOPRESERVATION
Sperm banking for medical and personal fertility preservation

SOCIAL FREEZING
Sperm banking for
long-term reproductive planning

ONCOFERTILITY
Personalised approach
to oncology patients

PREVENTIVE MEDICINE
Diagnostic and screening
of reproductive health

ANIMAL

Application

LIVESTOCK BREEDING
Healthy sperm for
efficient insemination

ENDANGERED SPECIES CONSERVATION
Undamaged sperm for
ZOO-based fertility programs

HUMAN
Application

ASSISTED
REPRODUCTION
Increase of sperm quality
and fertilization success

CRYOPRESERVATION
Sperm banking for medical and personal fertility preservation

SOCIAL FREEZING
Sperm banking for long-term reproductive planning

ONCOFERTILITY
Personalised approach
to oncology patients

PREVENTIVE MEDICINE
Diagnostic and screening
of reproductive health

ANIMAL

Application

LIVESTOCK BREEDING
Healthy sperm for
efficient insemination

ENDANGERED SPECIES
CONSERVATION

Undamaged sperm for
ZOO-based fertility
programs

SUCCESS to date

STRONG IP POSITION
AND PROACTIVE IP STRATEGY

  • Exclusive rights to core IP assets
  • Czech and European patents granted
  • New PCT applications in preparation
  • US patent application pending
  • European trademark registered

TRACTION & PROOF OF MARKET

  • 15+ years of underlying scientific research
  • Successful in vitro benchmarking studies completed
  • Two prototype iterations leading to MVP 2.0
  • Molecule 46 Sperm Separation Technology at TRL 4
  • Validation and endorsement from seven leading IVF clinics
  • Partnerships with three leading European livestock breeding companies
  • First paying customers in the animal reproduction market
  • 20+ qualified early-adopter opportunities in the pipeline

LOCAL & INTERNATIONAL
NON-DILUTIVE FUNDING

  • CzechInvest Technology Incubation Program
  • Central Bohemian Innovation Center (SIC)
  • EIT Health
  • European and US technology grant applications under review (€1M+)

PEOPLE

  • Scientific Advisory Board established, including a Nobel Prize Laureate
  • Multidisciplinary R&D team in place
  • Strategic hires identified to support commercialization and growth

AWARDS and MEDIA

2026

EU Seal of Excellence, Horizon Europe,
EIC pre-accelerator – Widening

Creative Heroes Award Czech Republic,
Category 1:1,000,000,000 – Impact on an International Scale

2025

Winner of the InnoStars Awards EIT Health

Bronze Award at Company of the Year, Capital City Prague

Silver Award at Start-up Disrupt Innovations United

Innovations United, Key-note and panellist

Czech Radio, Expert Interview

Czech Newspaper, Lead Article

Czech Academy of Sciences, Special Issue

Slovak Television, Live Broadcast 

2024

Gold Award at Start-up Accelerator,
Central Bohemian Innovation Center

Forbes, The most influential women of the Czech Republic

Forbes, Invited speaker at The Next Big Thing

Nominated for The Czech Scientist
of the Year – Innovation Technology
and EY Entrepreneur of the Year

2023

Forbes, Top Czech women scientist 2023

Ministry of Foreign Affairs, Czech women in World Science, TV and newspaper coverage, Czech Consulate, Istanbul, Turkey

2022

The Guardian, The Telegraph, BBC Science focus, Daily Mirror, The Tribune, Yahoo news

Czech TV, Prima CNN, Czech Radio,
and newspaper coverage

Czech Grant agency award for outstanding grant achievement

2021

Czech Press Office release,
The utilization of CD46 protein can accelerate the process of artificial insemination.

2025

Winner of the InnoStars Awards EIT Health

Bronze Award at Company of the Year, Capital City Prague

Silver Award at Start-up Disrupt Innovations United

Innovations United, Key-note and panellist

Czech Radio, Expert Interview

Czech Newspaper, Lead Article

Czech Academy of Sciences, Special Issue

Slovak Television, Live Broadcast 

2023

Forbes, Top Czech women scientist 2023

Ministry of Foreign Affairs, Czech women in World Science, TV and newspaper coverage, Czech Consulate, Istanbul, Turkey

2021

Czech Press Office release,
The utilization of CD46 protein can accelerate the process of artificial insemination.

PROUD to cooperate with